Studies have showcased profound potential for the acceptance of Stem Cell Therapy for Alzheimer’s, one of the studies indicated the use of human umbilical cord blood in 23 mice afflicted with Alzheimer’s. Mice infused with cord blood showed improved learning, memory, and motor function and markedly reduced Ab deposits compared to the control group who were not infused with cord blood. But there exists an enormous gulf between outcomes in mice and humans. In the case of humans, research is yet to showcase tangible results promising the development of the brain under stem cell treatment. To help patients suffering from Alzheimer’s, several studies are being thoughtfully carved that could help in the early recognition of Alzheimer’s. Early detection can help in improving the chances of help and recovery of lost brain functions.
Functional imaging research suggests that Alzheimer’s patients typically have reduced brain cell activity in certain regions. For example, studies with fluorodeoxyglucose and positron emission tomography indicate Alzheimer’s is often associated with reduced use of glucose in brain areas important in memory, learning, and problem-solving. An FDG-PET scan is considered a rational test for people with a recent diagnosis of dementia and recorded a cognitive decline of at least six months who meet the criteria for both Alzheimer’s and frontotemporal dementia.
One of the most active areas aimed at finding ways to diagnose Alzheimer’s in its earliest stages. Molecular strategies may select biological clues indicating Alzheimer’s is progressing before the disease changes the brain’s structure or function or takes an irreversible toll on memory, thinking, and rezoning. In addition, molecular imaging may offer a new strategy to monitor disease progression and assess the effectiveness of next-generation, disease-modifying treatments.
Cerebrospinal Fluid Tests
CSF is a clear fluid that revolves around the brain and spinal cord and cushions the brain. A normal adult has about 1 pint of CSF, which physicians can sample through a minimally invasive procedure called a lumbar puncture or spinal tap. According to research, Alzheimer’s disease in its early stages may cause changes in CSF levels of multiple markers such as tau and beta-amyloid, two markers from abnormal brain deposits strongly linked to Alzheimer’s.
A challenge in his testing is that analysis of biomarker levels in the sample can often vary significantly from institution to institution and across different platforms, the fluid is measured upon. For example, CSF tests, as of now, are used by dementia specialists to aid in the diagnosis of Alzheimer’s.
Even though amyloid plaques in the brain are a characteristic feature of Alzheimer’s disease, their presence alone cannot be used to diagnose the condition. Today a diagnosis of Alzheimer’s is based on evaluating several things, including the presence of Amyloid plaques.
Once Alzheimer’s has been diagnosed, here are some medicines that might help alleviate the situation.
Acetylcholinesterase (Ache) inhibitors
These medicines increase acetylcholine levels, a substance in the brain that helps nerve cells communicate with each other. These medicines can only be prescribed by specialists such as psychiatrists or neurologists. Donepezil, galantamine, and rivastigmine can be prescribed for patients with early to mid-stage Alzheimer’s disease. People respond to these inhibitors differently. Hence they should be specified over the counter only by a practicing psychiatrist.
This medicine is not an Ache inhibitor. It works by blocking the effects of an excessive amount of chemical in the brain called glutamate. Memantine is used for moderate or severe Alzheimer’s disease. It’s suitable for those who cannot take or are allergic to tolerate AchE inhibitors. Further, based on the symptoms, antidepressants can be prescribed to help the situation as well. In case of Stem Cell Therapy, early detection can profoundly help improve the chances of recovery of brain function. Medical service providers such as Global Stem Cell Care can help patients improve their conditions through supportive therapies, lifestyle changes, and cognitive therapies that help patients suffering from Alzheimer’s.