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    Get to Know All About Stem Cell Therapy for Rheumatoid Arthritis

    Rheumatoid arthritis (RA) it is an autoimmune syndrome that can cause joint pain and injury to the whole body. On both sides of the body, the joint injury that RA produces typically occurs. So if a joint in one of the arms or legs is affected, it is possible that the same joint in the other arm or leg will also be affected. This is one way that clinicians separate RA from other types of arthritis, such as osteoarthritis. (OA). Treatments function well when RA is detected early, so understanding the symptoms is crucial. From forms and signs to home remedies, diets, and other therapies, read on to learn everything you want to hear about RA.

    Orthopedics, a field of medical research predominantly affiliated with musculoskeletal diseases, is primarily concerned with locomotor conditions in the body, such as bones, ligaments, tendons, muscles, etc. The tissues are incredibly essential for the coordinated movements and healthy life we live; however, we may experience chronic pain, joint degeneration, fibromyalgia, muscle fatigue, and even reduced mobility in extreme cases due to rapid activation of inflammatory pathways within our body. As no definitive cure is provided by traditional medical research, regenerative medicine has investigated various methods of managing damage related to inflammatory pathways.

    Rheumatoid Arthritis Stem Cell Treatment in Delhi, India

    People are searching for stem cell therapy for Rheumatoid Arthritis in Delhi, India, but can’t seem to find the Best stem cell center or hospitals for Rheumatoid Arthritis at an affordable price. Global Stem Cell Care helps those patients to finding best hospitals for the Rheumatoid Arthritis stem cell treatment in Delhi, India

    Do you know about Rheumatoid Arthritis?

    Rheumatoid arthritis is a form of autoimmune disease that affects the joints and other body locations, causing chronic inflammation of the joints.

    For a longer period of time, neglect can lead to deformed and painful joints that are badly malfunctioning.

    Over time, the condition can also effect other organs other than the joints, such as the heart. Any of the signs that are widely related are:

    • Normal treatment-resistant rheumatoid arthritis,
    • Ineffective treatment of anti-inflammatory medications, including steroids,
    • Important decrease in joints’ functional ability,
    • Tropic Musculoskeletal System Disorders
    • Important deviations in immunological and hematopoietic problems

    Symptoms of Rheumatoid Arthritis

    With RA, there are times when symptoms get worse, known as flares, and times when symptoms get better, known as remission.
    Signs and symptoms of RA include:

    • Ache or soreness in more than one joint
    • Rigidity in more than one joint
    • Tenderness of more than one joint and swelling
    • For all sides of the neck, the same signs (such as in both hands or both knees)
    • Loss of weight
    • Fever
    • Tiredness or exhaustion
    • Deficiency

    Diagnosis of Rheumatoid Arthritis

    By evaluating signs, doing a physical examination, and conducting X-rays and diagnostic testing, Rheumatoid Arthritis is diagnosed. It is better to diagnose Rheumatoid Arthritis early, so that people with the disease can initiate therapy to delay or interrupt the development of the disease within 6 months of the onset of symptoms (for example, damage to joints). Diagnosis and successful therapies, especially in the treatment of inflammation suppression or regulation, can help minimize the adverse effects of Rheumatoid Arthritis.


    • Swelling and pain in various joints, especially those of the hands and feet
    • Stiffness in the morning which last around 45 minutes
    • Development of firm lumps under the skin near the joints
    • Deterioration of the cartilage and bone
    • Frequent infections
    • Anemia
    • Eye inflammation
    • Persistent inflammation
    • Fatigue
    • Morning stiffness that lasts up to 30 minutes
    • Stiffness, especially in the knees, ankles, hips, hands, and elbows
    • Tenderness, swelling, and redness in the joints
    • Symptoms that affect joints on both sides of the body
    • Less ability to use one or more joints
    • Decreased appetite
    • Poor weight gain and slow growth
    • Eye inflammation
    • Swollen, stiff, and painful joints in the knees, hands, feet, ankles, or other joints, which occur in the morning or after a nap
    • Warmth and redness in the joint

    The following factors can be the possible reasons for having rheumatoid arthritis:

    • Age– Rheumatoid arthritis affects adults of any age, although most people are diagnosed between 40 and 60. Around three-quarters of people with rheumatoid arthritis are of working age when they are first diagnosed.
    • Sex- This condition RA is two to three times more common among women than men.
    • Genetics– Rheumatoid arthritis develops because of a combination of genetic and environmental factors, such as smoking and diet. It is unclear what the genetic link is, but it is thought that having a relative with the condition increases your chance of developing it.
    • Weight– If the person is overweight, they have a greater chance of developing RA than a healthy-weight person.
    • Smoking– Cigarette smoking significantly increases the risk of having rheumatoid arthritis.
    • Diet– According to some studies, if you eat a lot of red meat and don’t consume much vitamin c, the individual may have an increased risk of developing rheumatoid arthritis.
    Physiotherapy
    Physiotherapy
    Also known as physical therapy and the primary goal of it is to keep you moving. It uses exercise and other methods to stimulate muscles, bones, and joints. The result is more strength, tone, and overall fitness. In the early stages of the disease, your physical therapist can check on your strength, fitness, and how well your joints work. They'll make an exercise plan to keep your joints as healthy as possible. If you have moderate or advanced rheumatoid arthritis, physical therapy can help you maintain or improve your strength and flexibility.
    Occupational Therapy
    Occupational Therapy
    OT aims to help the patients to help adapt to physical limitations so that they can successfully complete activities in their daily life. This therapy may improve RA symptoms in various factors. It improves your ability to function despite joint limitations, decreases pain, helps fight fatigue, assists the ability to perform activities independently, prevents symptoms from getting worse, and prevents deformities without straining or misusing any joints. An occupational therapist will help make modifications in patients’ lives to keep them active and increase mobility.
    Acupuncture
    Acupuncture
    Acupuncture is a type of Chinese traditional medicine that dates back thousands of years. Acupuncturists use fine needles at pressure points in various parts of the body. This treatment is said to relax the body and increase blood flow. The treatment is believed to release endorphins. These are natural hormones that reduce the feeling of pain. While acupuncture can relieve pain, it is unlikely to significantly reduce inflammation. Acupuncture should not be used as the sole treatment for RA but rather as an additional treatment in conjunction with RA disease-modifying medications.
    Dietary Modifications
    Dietary Modifications
    Rheumatoid arthritis (RA) can strike anyone at any age. RA is different from osteoarthritis, which is the natural wearing down of joints over time. RA occurs when your immune system attacks your joints. Foods that may help with RA symptoms have anti-inflammatory properties. They reduce inflammation in the body. Choosing anti-inflammatory foods and following the diet may improve RA symptoms. At the same time, trigger foods can make inflammation worse. A certain number of people with RA have reported that certain foods relieve or worsen RA symptoms.
    Gene Therapy
    Gene Therapy
    RA is a chronic inflammatory disease characterized by persistent joint swelling and the progressive destruction of cartilage and bone. The primary manifestations are pain, swelling, and limited joint motility due to inflammation of the synovial membrane. Gene therapy can provide stable, long-term expression of therapeutic proteins at the site of inflammation, thereby improving the treatment of RA and reducing costs related to the treatment with biologicals. Several gene therapy approaches have been developed and tested in animal models of arthritis.
    Hyperbaric Oxygen Therapy
    Hyperbaric Oxygen Therapy
    Hyperbaric oxygen therapy has become a standard of practice for RA in many countries. Clinical practice has proved that hyperbaric oxygen therapy has sound effects on analgesia, lowering blood sedimentation rate, stabilizing immunologic function, and strengthening the body’s resistance to eliminating pathogenic factors. It is also beneficial for the repair of diseased joints. HBOT can suppress inflammation due to either immune factors or infection. Moreover, daily hyperbaric oxygen therapy suppresses the inflammatory response even if the disease is fully developed
    • Intravenous administration
    • Liberation angioplasty
    • Intrathecal (lumber puncture)
    • Intraarterial
    • Surgical administration for stroke
    • Intramuscular
    • Subcutaneous

    Implantation

    The following is the structure that is followed during the implantation stage:

    Mechanism

    A non-invasive treatment that helps to restore compromised cells within the body is stem cell therapy. Based on patient conditions, mesenchymal stem cell therapy may be deployed systemically via IV or injected locally to reach particular sites.

    Inflammation targets stem cells.

    The medicinal applications of stem cells have been widely investigated as a possible treatment for different diseases. Over the last five years, the number of clinical trials performed with Mesenchymal Stem Cells has grown exponentially.

    Stem cells have a characteristic, inherent property that draws them to the body’s inflammation. Studies have shown that stem cells can rebuild weakened or diseased tissues, minimize inflammation, and enhance the health and quality of life of the immune system by stabilizing the immune system. Mesenchymal stem cells do this by altering the reconstruction of tissues by paracrine effects (cell signalling to modify current cell behavior) or direct cell-to-cell communication.

    Stem cell therapy offered by Global Stem Cell Care is the best-in-class stem cell treatment provider in India. The best stem cell hospitals in Delhi, India offer the most reliable treatment therapy provider.

    Rhumetoid Arthritis

    Get Stem Cell Therapy for Rheumatoid Arthritis

    Rheumatoid Arthritis can be improved with mesenchymal stem cell therapy as a chronic autoimmune inflammatory condition. There is an incredible potential for stem cells to transform into any cell in the body. Differentiation is called this method. To locate and restore weakened tissue in the body, stem cells may be delivered intravenously. Stem cells may be able to heal weakened tissue and decrease discomfort and improve mobility when used in Rheumatoid Arthritis patients.

    This suggests that in patients with autoimmune conditions, stem cells can be able to control or relax an imbalanced immune system. Data shows that mesenchymal stem cells had the capacity to immunosuppress (partially suppressing the immune system response). They can suppress alloantigens and mitogens from T-cell proliferation and prevent cytotoxic T-cells from growing in vitro.

    How Global Stem Cell Care Therapy Works ?

    Does stem cell therapy work for Rheumatoid Arthritis?

    Yes, therapy with stem cells can have a positive effect on patients with RA. The beneficial benefits of mesenchymal stem cells extracted from umbilical cord-tissue can be sustained for three years, with stable health results that have greatly increased the quality of life of RA patients.

    So can stem cell therapy cure Rheumatoid Arthritis?

    Although recent data have shown positive outcomes, stem cell therapy for Rheumatoid Arthritis should not be considered a “cure” (RA).

    However by reducing inflammation and stabilizing the immune system, mesenchymal stem cells can greatly benefit Rheumatoid Arthritis patients.

    VIP Treatment to Patients at Global Stem Cell Care

    •  The stem cell therapy for Rheumatoid Arthritis sessions given to the patients at Global Stem Cell Care takes place in the VIP treatment room that is in the advanced clinic.
    • 24*7 supervision is maintained on the patients by the efficient medical team.
    • Global Stem Cell Care highly recommends the patients stay for a minimum of 3 days in Hospital.

    Global Stem Cell care Treatment Procedure

    Day 1

    • Pick up from the Airport to the Hospital
    • Interaction between Dr and Patient, to clear all their doubts at that time
    • Admission procedure
    • Clinical examination & Lab test will be done prescribed by the doctor
    • Supportive Therapy

    Day 2

    • Global Stem Cell Care Procedure
    • Supportive therapies
    • Physiotherapy

     Day 3

    • Supportive Therapy
    • Physiotherapy
    • Discharging formalities
    • Drop back to the Airport

    Note

    • For Admission, carry the identity card (Passport/ Pan Card / Driving License)
    • Carry the hard copy of Patient reports

    Who should diagnose and treat RA?

    What to Expect from Stem Cell Treatment for Rheumatoid Arthritis?

    • To understand the potential of stem cell therapy for Rheumatoid Arthritis, first of all it is important to know a little more about stem cells and their role in the human body. To be sure, stem cells are present to one degree or another at all ages, within any part of the body. We have very high stem cell concentrations as children, which are responsible for repairing damage and providing cellular repair.

    • In our stem cells, other modifications take place over time, too. Most important, they are becoming less effective. Stem cells mature and die, as all other cells in the body. They are able to duplicate themselves, self-replicate and produce more of themselves, unlike most cells.

    • For many factors, this is important. Obviously, the older the patient, the less effective the healing and regeneration of their own stem cells would be. It also refers, however, to certain types of stem cell therapy. Autologous stem cells are extracted from the body, replicated and then reinjected into the body in a laboratory or in an office.

    • Allogeneic stem cells, on the other hand, are distinct. This are harvested from freely banked umbilical cord blood and tissue that has been carefully screened. There are young and extremely energetic cells. They also do not have any mutations that could degrade performance. They are eventually, and perhaps most importantly, transparent to the immune system.

    • The RA sufferers are always looking for reliable ways and treatments to help with treating a particular disease and ailment.

    Possible Improvement

    Stem cell therapy is extremely promising for curing rheumatoid arthritis. In addition to a long-lasting medication that alleviates effects, there is the possibility for a solution that might potentially reverse the disease for long stretches at a time. Stem cell therapy, however is not approved by the FDA, so any treatment options open to you will only be experimental.
    It’s obvious that you work with alongside a physician who better understands the overall importance of using allogeneic stem cells, rather than autologous stem cells.

    Frequently Asked Questions

    A. Now we know a lot about what triggers RA and how it can be handled. Although we are currently unable to heal it, joint injury will now be avoided. The early implementation of disease-modifying antirheumatic drugs is accomplished by this (DMARDs). In order to prevent joint erosion and long-term limitation of operation, these are important to obtain rapid control of the disease.

    A. The actual cause of Rheumatoid Arthritis is unknown, but it is usually thought to be majorly triggered by environmental factors. In individuals with a predisposition to the disorder through genetics. Nevertheless, though some patients recall a viral-type infection before RA started, most do not. No unique infectious agent has been discovered to date. (Some antibiotics may strengthen RA a little but their advantages tend to come from their anti-inflammatory activity, not their actions to kill bacteria.) In the early development of rheumatoid arthritis, cigarette smoking and oral inflammation (gingivitis) have been involved.
    In the development of RA, genetic factors play a major role. Genetic variables mean that a person has genes that put him or her at risk for RA and that those genes have been turned on (meaning expressed in cells). But it is the interaction with a genetically predisposed individual with an environmental agent that appears to initiate the RA trait of self-perpetuating inflammation. While the significance of genetics is obvious, it must also be taken into consideration that health factors affect it all.

    A. The immune system plays a major role in development of joint inflammation and damage, fatigue, and the feeling that you have a chronic viral illness. The immune system is made up of body-protecting cells and antibodies. In normal people, these help to fight off invading infectious agents. In RA, however, something goes awry, and the immune system appears to be directed against the person’s tissues. Thus, it is called an autoimmune disorder.

    A. The major symptoms of the joint are due to the inflammatory state and include discomfort, stiffness, redness, hot, and reduction of the range of motion of the joints affected. In what is considered a symmetric pattern, the joint pains in RA behave in a particular way and influence different joints on both sides of the body.
    That is, if your left knee is affected, your right knee will possibly also be affected. Tiny hand and foot joints, elbows, shoulders, and ankles are the joints that are most likely to be affected. The external symptoms of inflammation indicate a potentially dangerous mechanism of pathology that can lead to bone, cartilage, and soft tissue such as tendons being damaged. This can cause deformities and physical disabilities if left untreated.

    A. In some patients with RA, diet may play a part. A well-balanced diet, though is the best medicine for everyone. To decide if consuming one form of food is generally associated with a flare of RA, patients should keep a diary. A trial of refusing the food is fair if that is the case. To endorse maintaining a healthier weight, data is accumulating. Any reports indicate that less disease-related effects are linked with eating fish two or three days a week.

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