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    Get to Know All About Stem Cell Therapy for Lymphoma

    Lymphoma is a cancer that starts in the cells of the immune system, called lymphocytes, that battle infection. The lymph nodes, spleen, thymus, bone marrow, and other areas of the body are in these cells. Lymphocytes shift when you have lymphoma and develop out of control.

    Two major forms of lymphoma exist:

    • Non-Hodgkin: This type is normal in most patients with lymphoma.
    • Hodgkin: Different types of lymphocyte cells are active in non-Hodgkin and Hodgkin lymphoma. Each type of lymphoma develops at a different pace and responds to therapy differently.

    Lymphoma is highly treatable, and depending on the type of lymphoma and its level, the outlook can vary. Your doctor will assist you in seeking the best medication for your condition type and stage. Leukemia differs from lymphoma. Each of these cancers begins in a cell of a particular kind. Lymphoma begins with lymphocytes that battle infection. In the blood-forming cells inside the bone marrow, leukemia begins.

    Lymphoma Bone Marrow Therapy in India

    Bone marrow treatment for lymphoma in Delhi is a complex process that requires specialized care. Depending on the type and severity of the condition, a regimen of a bone marrow transplant, chemotherapy, immunotherapy medications, and/or radiation therapy may be necessary for successful treatment.

    In order to provide the best possible care, doctors and medical professionals work together to develop a plan that is tailored to each individual patient’s needs. With the right tools and support, lymphoma patients in India can rest assured that they will receive the best care available.

    Do you Know About Lymphoma?

    Doctors don’t know what’s behind the lymphoma. But it starts as a genetic defect is produced by a disease-fighting white blood cell called a lymphocyte.

    The mutation tells the cell to replicate easily, resulting in numerous diseased lymphocytes that begin to multiply. The mutation also allows the cells to carry on surviving while all normal cells would die. This causes the lymph nodes to contain too many diseased and ineffective lymphocytes and causes the lymph nodes, spleen, and liver to swell.

    Factors of Vulnerability. Factors that can raise lymphoma risk include:

    Your generation. In young adults, some forms of lymphoma are more common, while in persons over 55, others are more commonly diagnosed.

    To be male. Males are significantly more likely than females to develop lymphoma.

    Getting an immune system compromised. In patients with disorders of the immune system or in people who take medications that inhibit their immune system, lymphoma is more likely.

    Symptoms of Lymphoma

    Lymphoma warning signs include:

    • Swollen glands (lymph nodes) that are mostly painless in the throat, armpit or groin
    • Coughing
    • Shortness of Breath
    • A fever
    • Sweats at Night
    • Tiredness
    • The lack of weight
    • Itching
    • Many of these symptoms may be early signs of other ailments as well. In order to figure out for sure if you have lymphoma, visit the doctor. Stem Cell treatment for the overall improvement of health is an ideal and most preferred treatment.

    Diagnosis

    Before you have any tests, your doctor will want to know:

    A physical examination, including screening for swollen lymph nodes, will be performed by the doctor. This symptom doesn’t mean there’s cancer in you. Most of the time, an inflammation causes swollen lymph nodes—unrelated to cancer. You may be given a biopsy of the lymph node to scan for cancer cells. A specialist may scrape more or half of a lymph node or use a needle to remove a small amount of tissue from the infected node for this procedure.

    To better detect, stage, or treat lymphoma, you may also have either of these tests:

    Aspiration or biopsy of the bone marrow. To look for lymphoma cells, the doctor uses a needle to extract fluid or tissue from the bone marrow—the spongy part within the bone where blood cells are formed.

    X-ray chest. It can be achieved to produce images of the interior of the chest using low levels of gamma radiation.

    MRI. Using strong magnets and radio waves, a technician can produce pictures of organs and structures within the body.

    PET Scan. In order to scan for cancer cells in the body, this imaging procedure uses a radioactive material.

    Test of molecules. In order to help the doctor sort out what sort of lymphoma you have, this procedure is used to find modifications to genes, proteins, and other substances in cancer cells.

    Stem cell therapy for Lymphoma is offered by the best and the most reliable stem cell hospitals.


    • Swollen or enlarged lymph nodes
    • Cough and issues while breathing
    • Unexpected weight loss
    • Tiredness feeling and coldness
    • Inflated abdomen
    • Feeling full after eating only a small portion of food
    • Pain and unwanted pressure in the chest
    • Swelling in the neck, groin and armpits
    • Constant fatigue
    • Night sweats
    • Unexplained chills or fever
    • Breathing problems due to enlarged lymph nodes
    • Weight loss without intentional effort
    • Itching that is extremely intense

    The exact cause of lymphoma remains uncertain; however, it is believed to originate from a genetic mutation in a white blood cell, known as a lymphocyte, that leads to the cell multiplying abnormally and rapidly. This subsequently causes an accumulation of diseased lymphocytes.

    The mutation also allows the cells to go on living when other normal cells would die. This causes too many diseases and ineffective lymphocytes in your lymph nodes and causes the lymph nodes, liver and spleen to swell.

    However, certain factors may increase one’s likelihood of developing genetic mutations, which lead to lymphoma. These are known as risk factors. These factors generally work by accelerating the rate of natural mutation.

    Risk factors that increase the chance of developing lymphoma:

    • Individual’s age
    • If you have any family history
    • Emerging certain infections
    • Gender- higher in male
    • Having a weakened immune system
    • Being overweight

    Global Stem Cell Care is a trusted and best hospital for lymphoma treatment in India. Since its commencement, we have been developing and refining our bone marrow treatment for lymphoma protocols with the understanding that stimulation of the stem cells through a range of adjunct therapies is essential for maximizing their regenerative properties.

    Acupuncture
    Acupuncture
    The use of acupuncture involves the insertion of extremely fine needles into specific points located on the surface of the body, known as acupuncture points. This has been used as a means of managing pain, as well as relieving the side effects of chemotherapy, such as nausea and vomiting and fatigue associated with lymphoma treatment in India.
    Medical Nutrition Therapy
    Medical Nutrition Therapy
    Nutrition therapy is utilized following a bone marrow transplant for lymphoma, with the aim of helping cancer patients attain the necessary nutrients for maintaining body weight and strength, sustaining healthy bodily tissue, and combating infection. The eating habits of cancer patients may vary drastically from the standard healthy eating requirements.
    Physiotherapy
    Physiotherapy
    Patients undergoing bone marrow transplant for lymphoma may experience fatigue, reduced strength and flexibility and instability. Our physical therapist can provide assistance in recovering well-being during and after the treatment program. The implementation of the exercise plan in combination with manual techniques can improve quality of life and make the post-bone marrow transplant in lymphoma and other cancers more manageable.
    Aqua Therapy
    Aqua Therapy
    Hydrotherapy or aqua therapy has been demonstrated to potentially increase immune function and facilitate the transfer of essential nutrients and waste products. It is suggested to end hot showers with 1 to 2 minutes of cold-water spray in order to stimulate lymphatic flow. As such, it is recommended to seek medical advice prior to initiating a hydrotherapy regimen.
    • Intravenous administration
    • Liberation angioplasty
    • Intrathecal (lumber puncture)
    • Intraarterial
    • Subcutaneous
    • Surgical administration for stroke
    • Intramuscular

    Implantation

    The following is the structure that is followed during the implantation stage:

    MECHANISM

    The main objective of bone marrow treatment for lymphoma is to substitute the cancerous cells present in a patient’s bone marrow with fresh, healthy blood-forming stem cells for the purpose of treating cancer.

    Our specialist utilizes two different forms of bone marrow transplant for lymphoma, which are allogeneic and autologous transplantation. In the allogeneic process, they require the collection of bone marrow or stem cells either from a non-related donor or from a partially mismatched relative, while on the other hand, autologous involves the use of a patient’s own marrow before chemotherapy. Additionally, immunosuppressive therapies must be administered in order to facilitate successful transplantation and proliferation of the transplanted cells.

    Following the successful elimination of cancerous cells from the bone marrow, the donor’s healthy bone marrow stem cells are administered to the patient via the implantation process, which may include various types of techniques. Afterwards, these cells migrate to the bone marrow, where they initiate the production of healthy new blood cells.

    In order to maximize the chances of successful transplantation, we endeavour to locate a donor whose genetic makeup is an ideal match for the patient. This could be an immediate family member or even a stranger. Once found, healthy stem cells are transplanted, allowing them to replicate and generate the new blood cells and bone marrow the body requires.

    Lymphoma

    Get Stem Cell Therapy for Lymphoma

    The medication you get depends on the form and level of lymphoma you have.

    In the case of non-Hodgkin lymphoma, the primary treatments are:

    • Chemotherapy that destroys cancer cells using medications
    • Radiation treatment that kills cancer cells using high-energy rays
    • Immunotherapy, using the immune system of the body to attack cancer cells

    Targeted treatment that activates lymphoma cell components to curtail their development

    The below are the key therapies for Hodgkin’s lymphoma:

    • Chemotherapy
    • Radiation treatment
    • Immunotherapy

    You could get a stem cell transplant if these therapies don’t work. You’ll get very high doses of chemotherapy first. This procedure removes cancer cells but also eliminates the stem cells that make new blood cells in the bone marrow. You will have a stem cell transplant following chemotherapy to replace the ones that have been killed.

    Two kinds of stem cell transplants are possible:

    • An autologous transplant uses stem cells of your own.
    • Using stem cells taken from a donor is an allogeneic transplant.

    Stem cell treatment by the best and the most reliable facility like Global Stem Cell Care, ensures you have the best treatment for your chronic disease or any ailment.

    How Global Stem Cell Care Therapy Works ?

    There are 2 main types of stem cell transplants (SCTs) based on where the stem cells come from. The patient’s own stem cells was used in an autologous stem cell transplant. In the weeks before surgery, they are extracted several times. The cells are frozen and preserved until the person seeks medication (high-dose chemo and/or radiation) and then an IV is returned to the blood of the patient (catheter in the vein).

    The stem cells in an allogeneic stem cell transplant originate from somewhere else (a donor). This is usually a brother or sister, but an unrelated donor or umbilical cord blood may be the source. The tissue type of the donor (also known as the HLA type) has to complement the tissue type of the recipient as closely as possible to help prevent the possibility of significant transplant complications. Regardless of the source, before they are required for the transplant, the stem cells are frozen and processed.

    In order to combat lymphoma, autologous SCTs are more commonly used than allogeneic SCTs. Still, if the lymphoma has progressed to the bone marrow or blood, using the patient’s own cells will not be a choice.

    For lymphoma, allogeneic transplants are less commonly used because they may have serious side effects that make them difficult to handle, especially in patients that are older or have other medical issues. A matched donor can also be difficult to identify.

    A stem cell treatment by a specialized facility offers reliable transplant. It is a difficult procedure otherwise to handle. There can be some side effects that are life-threatening. If physicians believe a person will benefit from a transplant, it could be performed at a cancer facility where the nurses have familiarity with the treatment and the rehabilitation process management. Global Stem Cell Care has been providing the best of treatment to the patients who are suffering from this condition, and through the stem cell treatment, their symptoms have also improved.

    VIP Treatment to Patients at Global Stem Cell Care

    • The therapy sessions given to the patients at Global Stem Cell Care occur in the VIP treatment room in the advanced clinic.
    • 24*7 supervision is maintained on the patients by the efficient medical team.
    • Global Stem Cell Care highly recommends the patients stay for a minimum of 3 days in Hospital.

    Global Stem Cell care Treatment Procedure

    The treatments that take place in Global Stem Cell Care are of 3 days. The treatment protocol is safe and non-invasive. The patients can travel the next day. The following is the day-wise schedule for the patients.

    • Pick up from the Airport to the Hospital
    • Interaction between Dr and Patient, to clear all their doubts at that time
    • Admission procedure
    • Clinical examination & Lab test will be done prescribed by the doctor
    • Supportive Therapy
    • Stem cell Procedure
    • Supportive therapies
    • Physiotherapy
    • Supportive Therapy
    • Physiotherapy
    • Discharging formalities
    • Drop back to the Airport
    • For Admission, carry the identity card (Passport/ Pan Card / Driving License)
    • Carry the hard copy of Patient reports

    What to Expect from Stem Cell Treatment for Lymphoma?

    • Stem cells are primarily distinguished by the characteristics of unrestricted self-renewal, which preserves and extends the undifferentiated cell pool throughout the host’s lifespan, and multi-lineage differentiation, which generates progeny of various mature tissue generation and regeneration phenotypes. These properties of stem cells are strictly regulated in normal growth, but their modification may lead to tissue generation and regeneration.

    • In particular, it has been proposed that tumors are formed from mutant stem cells, the so-called cancer stem cells, since stem cells and certain cancer cells share self-renewal and differentiation capacities.

    • While this theory was postulated in early literature, definitive confirmation of its presence came from recent leukemia experiments, where only a small subset of cells could start, regenerate and sustain leukemia following transplantation into immunocompromised mice within the total tumor cell population. A variety of cancer stem cells have been detected in a growing number of epithelial tumors using similar functional methods, including breast, prostate, pancreatic, and head and neck carcinomas, all of which have been characterized by cell-surface glycoprotein expression CD44.9 Another cell surface marker, glycoprotein CD133, has been classified as tumor-initiating brain and colorectal cells.

    • In addition to improving our present view of cancer biology, the idea of cancer stem cells can also have significant implications for cancer diagnostics and therapeutics. For example, as molecular predictors of clinical outcome, gene expression profiles associated with the stem/differentiation states of tumors may be used. In comparison, glioblastoma and breast cancer research support the belief that stem cell cancer is more resistant to radiotherapy and chemotherapy-induced apoptosis, which makes it easier for these cells to survive and produce relapsed tumors. Chronic myeloid leukemia (CML), where the tyro-sine kinase inhibitor imatinib has replaced IFNa as the standard treatment, is a prototypical example of a stem cell disease.

    • However, as a consequence of this compound being active against differentiated CML progenitors while providing minimal efficacy against quiescent CML stem cells, clinical trials did not demonstrate predicted cure rates with the use of imatinib. Consequently, after the medication was withdrawn, many patients in apparent absolute molecular recovery relapsed. These results indicate that a reservoir responsible for disease relapse, a condition that could also exist in other cancers, may represent CML stem cells.

    Frequently Asked Questions

    Lymphoma is a type of cancer that attacks lymphocytes, which are the white blood cells that battle infection in the body. Lymphocytes are found within the lymph nodes, bone marrow, spleen and thymus, as well as in other areas of the body, and are a vital component of the immune system.

    Two major forms of lymphoma exist: non-and Hodgkin’s Hodgkin’s. In a particular form of lymphocyte, every disease develops, progresses at a different pace and needs a complex variety of therapies. While both disorders are equally uncommon, non-Hodgkin happens more frequently than Hodgkin does.

    Lymphoma is often associated with leukemia, a particular type of cancer that affects the blood-forming cells in the bone marrow, causing the lymphocytes to shift and quickly expand out of control. While no disorder can be identified on the basis of the symptoms alone, it is crucial that the signs of both can be recognized.

    Differences Between Hodgkin & Non-Hodgkin Lymphoma

    Hodgkin lymphoma and non-Hodgkin lymphoma may easily be mistaken with two similar-sounding titles. Lymphoma, a type of white blood cell that plays an essential role in the immune system, is a form of cancer that affects lymphocytes. The key distinction in these two lymphatic cancer types is the form of lymphocyte that is impacted. Hodgkin’s lymphoma is characterized by the presence of Reed-Sternberg cells that can be detected by a doctor using a microscope. These cells are not involved in non-Hodgkin lymphoma.

    Lymphoma, or lymphatic cancer, is a type of cancer that affects a group of lymphocytes called white blood cells. Although there are no general screening guidelines for this type of cancer, if you start having lymphoma-related symptoms, such as enlarged lymph nodes, exhaustion, and weight loss, you can see a doctor.

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