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    Get to Know All About Stem Cell Therapy for Down Syndrome

    Down syndrome is a genetic disease that is caused by an extra full or a partial copy of chromosome 21, which results in irregular cell division. The behavioral variations and facial characteristics of the Down syndrome is caused by the additional genetic material. Down syndrome differs among people in the level of severity, causing some form of either permanent intellectual impairment or some form of delay in growth. This is the most predominant hereditary chromosomal defect in children and the cause of learning disorders. Some physiological anomalies, including cardiac and gastrointestinal conditions, are also commonly induced. Better knowledge of Down syndrome and early interventions will dramatically enhance the quality of life of children and adults with this disease and help them live meaningful lives.

    Do You Know About Intellectual Disability?

    Often known as trisomy 21, Down syndrome or Down’s syndrome is a developmental condition caused by the involvement of all or half of a third copy of chromosome 21. It is typically associated with physical development defects, slight to moderate learning disability, and distinctive facial features. A young adult with Down syndrome has an average IQ of 50, similar to the emotional potential of an 8- or 9-year syndrome.

    In addition, the parents of the affected child are genetically normal. In 20-year-old women, the risk rises from fewer than 0.1 percent to 3 percent in those aged 45.

    The extra chromosome is believed to arise through chance, with no known behavioral interaction or environmental cause that affects the probability. Down syndrome may be detected by prenatal tests throughout infancy.

    Global Stem Cell Care has been providing the best of treatment to the patients who are suffering from this condition, and through the stem cell treatment, their symptoms have also improved.

    Stem cell treatment is a cure for this condition that helps replace the damaged cells. Global Stem Cell Care has the best team that works for the effective treatment of this medical condition.

    Symptoms of Down Syndrome

    A person with Down syndrome is an individual and there can be minor, moderate or serious intellectual and developmental disorders. Some individuals are well, and others have significant health issues, such as extreme heart defects.

    Down syndrome infants and adults have distinct facial characteristics. While not all persons with Down syndrome have the same characteristics, some of the most common characteristics include:

    • Flattened Face
    • Small-sized head
    • Short-cut collar
    • Tongue Protruding
    • Upward lids with slanting eyes (palpebral fissures)
    • Unusually rounded ears or smaller ones
    • Weak sound in the muscles
    • Broad, short hands with a single palm crease
    • Relatively small digits and little feet and hands
    • Excessive mobility
    • Small white spots called Brushfield spots on the colored portion (iris) of the eye
    • Short height: short height
    • Infants with Down syndrome can have an average height, but they usually develop slower and stay shorter at the same age as most infants.


    The risk or chances of a woman having a baby with Down syndrome may be demonstrated by screening tests. But these tests can’t say or diagnosis whether the infant has Down syndrome for sure.

    If the child has Down syndrome may be identified or diagnosed by screening testing.

    The types of procedures, benefits and drawbacks, advantages and risks, and the meaning of the findings will be addressed with your health care provider. Your physician can suggest that you meet with a genetic counselor, if necessary.


    During breastfeeding, screening tests

    Down syndrome screening is provided as a standard part of prenatal treatment. While screening tests can only assess the risk of carrying a baby with Down syndrome, they can help you make more precise medical testing choices.


    The first trimester combination test and the integrated screening test involve screening tests.


    Combined test for the first trimester

    The combined examination for the first trimester, which is completed in two steps, includes:

    Blood Test. This blood test tests the plasma protein-A (PAPP-A) levels associated with pregnancy and the pregnancy hormone known as human chorionic gonadotropin (HCG). Abnormal PAPP-A and HCG levels may suggest an issue with the infant.

    Nuchal Translucency Test. An ultrasound is used to measure a small region on the back of your baby’s neck during this procedure. This is known as the nuchal screening test for translucency. In this neck tissue, more fluid than average appears to accumulate when anomalies are present.

    A doctor or genetic counselor will predict the risk of raising a baby with Down syndrome by using your age and the findings of a blood test and ultrasound.

    • Distinctive facial features
    • Mild to moderate intellectual disabilities
    • Heart, kidney and thyroid issues
    • Less responsive to stimuli
    • Vision and hearing impairment
    • An inwardly curved little finger
    • Wide space between the great and second toe
    • Lower IQ
    • Slower Speech
    • Small ears
    • Eyes that tend to slant up
    • A flattened face
    • White spots on the iris of the eye
    • Shorter height
    • Flattened nose and face
    • Upward slanting eyes
    • Wide shorts hands with short fingers
    • Excess skin at the nape of the neck
    • The decreased muscle tone at birth

    Down syndrome is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone in infancy. All affected individuals experience cognitive delays, but the intellectual disability is usually mild to moderate.

    Down syndrome results when abnormal cell division involving chromosome 21 occurs.

    Down syndrome is caused by an abnormality in cell division which results in an extra partial or complete chromosome 21. This extra genetic material is what leads to the characteristic features and developmental problems associated with the syndrome.

    1. Trisomy 21: About 95 per cent of the time, Down syndrome is caused by trisomy 21 — the person has three copies of chromosome 21, instead of the usual two copies, in all cells. This is caused by abnormal cell division during the development of the sperm cell or the egg cell.
    2. Mosaic Down syndrome: In this rare form of Down syndrome, a person has only some cells with an extra copy of chromosome 21. This mosaic of normal and abnormal cells is caused by abnormal cell division after fertilisation.
    3. Translocation Down syndrome: Down syndrome can also occur when a portion of chromosome 21 becomes attached (translocated) onto another chromosome before or at conception. These children have the usual two copies of chromosome 21, but they also have additional genetic material from chromosome 21 attached to another chromosome.
    This treatment can play a significant role in managing children with down syndrome. The aim of treatment is to assist people in living as independently as possible. Interventions are based on the individual’s physical and intellectual needs, as well as their personal strengths and limitations. Some common issues that physiotherapists will address include delayed developmental milestones, balance issues, decreased strength, reduced levels of physical activity, issues with sensation and reduced mental health and emotional well-being.
    Occupational Therapy
    Occupational Therapy
    This therapy plays a vital role within the multidisciplinary team in treating individuals with Down syndrome. Occupational therapists are able to provide practical support and advice, enabling individuals with Down syndrome to live more independent lives. Occupational Therapists can help individuals with Down syndrome by breaking down tasks into smaller steps and then teaching them how to complete each step-by-step task. Occupational therapists can also provide appropriate aids and adaptations to assist with the completion of skills.
    Speech Therapy
    Speech Therapy
    Children with Down syndrome often have difficulties with their speech, language and communication skills. It is noticed that some children with Down syndrome start gesturing and using signs to communicate before they learn to use speech. This is basically the development of non-verbal skills before using verbal skills for communication. In this therapy, speech therapists follow the total communication approach, which means a combination of verbal and non-verbal to help the child improve their communication skills.
    This therapy is a method that can offer physical, mental and psychosocial improvements in people with down syndrome. These improvements are due, among other things, to the positive effect that hydrotherapy has on the respiratory system of individuals with down syndrome. The exceptional properties of the aquatic environment augment interventions for patients with neurological or musculoskeletal conditions. Aquatic therapy embraces various techniques that permit patients to improve their balance, muscle strength, and body mechanics.
    Diet Counselling
    Diet Counselling
    Infants and children with Down Syndrome can have feeding and drinking difficulties. A smaller oral cavity and low muscle tone in the facial muscles can be contributing factors. In addition, the tongue may appear more prominent due to a high-arched palate, a smaller oral cavity and reduced muscle tone in the vernacular. Diet and nutrition play a huge role in how the human body works, particularly when it comes to carrying out processes such as neurological development. This healthcare plan will assist in the treatment of the patient and help them return to their best health faster.
    • Intravenous administration
    • Liberation angioplasty
    • Intrathecal (lumber puncture)
    • Intraarterial
    • Subcutaneous
    • Surgical administration for stroke
    • Intramuscular


    The following is the structure that is followed during the implantation stage:


    Researchers and doctors hope stem cell studies can help to:

    • Increase awareness about how illnesses arise. Researchers and physicians may better understand how diseases and conditions grow by seeing stem cells mature into cells in bones, heart muscles, nerves, and other organs and tissues.
    • Generate healthy cells to replace diseased cells (regenerative medicine). Stem cells can be directed to become unique cells that can be used in individuals to rebuild and heal sick or injured tissues. Those of spinal cord injury, type 1 diabetes, Parkinson’s disease, amyotrophic lateral sclerosis, Alzheimer’s disease, heart disease, stroke, fires, tumors, and osteoarthritis are individuals that can benefit from stem cell treatments. Stem cells may have the ability to be grown for transplant and regenerative medicine to become new tissue. Researchers aim to advance the awareness on stem cells and their uses in transplant and regenerative medicine.

    Test new drugs for safety and effectiveness. Researchers can use certain types of stem cells to assess the medications for efficacy and consistency before using investigational drugs in persons. For cardiac toxicity testing, this method of testing would most likely first have a clear effect on drug production first. The feasibility of using human stem cells that have been programmed into tissue-specific cells to research new drugs is a recent field of research. The cells must be programmed to acquire the properties of the type of cells targeted by the drug in order for the testing of new drugs to be accurate. Techniques continue to be studied to program cells into particular cells. For instance, to test a potential drug for a nerve disorder, nerve cells may be produced. Tests could show whether there was any impact of the new drug on the cells and whether the cells were damaged.

    Down Syndrome

    Get Stem Cell Therapy for Down Syndrome

    The technology of stem cells offers lots of innovative ways to cure diseases. Most of the conditions that is referred to as untreatable is Down syndrome. So far, but for physiotherapy and special education, there is no appropriate cure for Down syndrome. However, only children of Down syndrome may be supported at a certain extent through physiotherapy and special education. For treating people with Down syndrome, neural stem cell transplantation therapy is used. With neural stem cell transplantation treatment, 300 Down syndrome patients have been treated. The age of the patient is from 8 months to 8 years. Most patients displayed varying degrees of change in intellectual growth, gait, voice, muscle power, and velocity of reaction.

    Stem Cell Treatment is a highly effective treatment methodology through which the damage that has been done to the brain can be repaired through the regeneration of nerve tissues.  Through stem cell treatment, there is the regeneration of nerve tissues, blood supply improvements, and reduction in inflammation. Global Stem Cell Care provides the best treatment for Down Syndrome that shows improvement in the child.

    How Global Stem Cell Care Therapy Works ?

    Stem cells are the raw materials of the body, cells from which all other cells are produced with special functions. Stem cells differentiate to form more cells called daughter cells under the proper conditions in the body or laboratory.

    These daughter cells either become new stem cells (self-renewal) or become differentiated cells (differentiation) with a more unique function, such as blood cells,

    nerve cells, heart muscle cells or bone cells. In the body, no other cell has the inherent capacity to produce new kinds of cells. Stem cell therapy is a regenerative one through which the damaged nerve cells can be removed from the patient. F

    Glurthermore, support is provided to the neurons and oligodendrocytes that are remaining. global Stem cell Care has the best medical team for the treatment of Down Syndrome through which

    the regeneration of the nerve tissues in the patient is achieved.

    VIP Treatment to Patients at Global Stem Cell Care

    • The therapy sessions given to the patients at Global Stem Cell Care occur in the VIP treatment room in the advanced clinic.
    • 24*7 supervision is maintained on the patients by the efficient medical team.
    • Global Stem Cell Care highly recommends the patients stay for a minimum of 3 days in Hospital.

    What to Expect from Stem Cell Treatment for Intellectual Disability?

    • Using stem cells or their equivalents, stem cell therapy, also known as regenerative medicine, facilitates the repair response to diseased, dysfunctional or wounded tissue. It is the process of organ transplantation which uses cells, which are small in quantity, instead of donated organs. In a lab, researchers grow stem cells.

    • In order to specialize in different types of cells, such as heart muscle cells, blood cells or nerve cells, these stem cells are manipulated. You will then insert the advanced cells into an individual.

    • If the child has heart disease, for example, the cells could be inserted into the muscle of the heart.

    • The healthy heart muscle cells transplanted will then lead to the reconstruction of damaged heart muscle. Researchers have also demonstrated that people can rebuild cardiac tissue in adult bone marrow cells directed to become heart-like cells, and further research is underway.

    • Global Stem Cell Care provides the best medical treatment to patients suffering from Down Syndrome. The treatment methodologies followed by the medical team of Global Stem Cell Care has no side effects as they provide the best healing to the patients. The testing is done during the treatment also. Research is being done on the efficacy of Stem Cell Therapy, and for that, the data is required for future prognosis to know the treatment after-effects on the patient.

    • It is sure to help improve the condition of Down Syndrome.

    Possible Improvements

    You want to be able to make educated decisions on therapy that will help your little one succeed if your child is born with Down syndrome. Because Down syndrome affects anyone who has it in varying respects, there is no one-size-fits-all care strategy. Yet doctors do know that the more likely they are to live up to their full potential, the sooner kids get treatment. From crawling and walking to communicating to learning how to be social, the child can need support in various ways. In kindergarten, they will even require special care. And they may have medical conditions that require treatment on a daily basis. It is sure to help improve the condition of Down Syndrome.

    Frequently Asked Questions

    Down syndrome is a genetic disorder that causes physical and intellectual developmental delays. It occurs in one out of every 700 live births or so. There is an additional copy of the 21st chromosome in individuals with Down syndrome that affects some or all cells. It is a chromosomal disorder that occurs most often. Down syndrome is not associated with ethnicity, nationality, religion or socio-economic status. The most important fact about people with Down syndrome to know is that they are more like others than they are distinct.

    Down syndrome is usually identified at birth or shortly thereafter. Initially the diagnosis is based on physical characteristics that are commonly seen in babies with Down syndrome. Signs of Down Syndrome may manifest in a variety of ways. Low muscle tone, a single crease across the palm of the hand, a slightly flattened facial profile, and an upward slant to the eyes may all be indications of this condition. The diagnosis must be confirmed by a chromosome study known as a karyotype.

    Usually, Down syndrome is caused by an error called non-disjunction in cell division. Why this is happening is not known. It is known, however, that the mistake occurs at conception and is not linked to anything done during pregnancy by the mother. Statistically, as maternal age advances, the incidence of Down syndrome increases. 80 percent of children with Down syndrome, though, are born to mothers under the age of 35.

    Beyond the normal pediatric conditions, many kids with Down syndrome have health problems. Around 40 percent of kids have heart defects that are congenital. In order to detect any severe heart complications that may be present, it is very important to perform an echocardiogram on all newborns with Down syndrome. Few heart diseases need surgery, although others simply need close supervision. There are increased incidences of pneumonia, gastrointestinal, eye and hearing issues in children with Down syndrome, as well as thyroid and other medical disorders. Many children and adults with Down syndrome, though, may lead healthier lives with proper medical attention.

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