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Get to Know All About Stem Cell Therapy for Bone Marrow Transplant
In order to restore your weakened or sick bone marrow, a bone marrow transplant is an operation that infuses new blood-forming stem cells into your body. A stem cell transplant is also considered a bone marrow transplant.
If your bone marrow stops functioning and doesn’t produce sufficient healthy blood cells, you might need a bone marrow transplant.
Cells from your own body (autologous transplant) or from a donor may be used for bone marrow transplants (allogeneic transplant).
A bone marrow transplant is a surgical procedure to restore a bone marrow that has been weakened or lost as a result of injury, cancer, or chemotherapy. This treatment involves blood stem cell transplantation, which moves to the bone marrow where new blood cells are formed and encourages new marrow development.
The spongy, fatty tissue between the bones is bone marrow. This produces the following portions of the blood:
- Red blood cells that hold nutrients and oxygen in the body
- White blood cells that combat infections
Immature blood-forming stem cells known as hematopoietic stem cells, or HSCs, also comprise bone marrow. Many cells are already segregated and only copies of themselves can be produced. These stem cells, though, are unspecialized, ensuring they have the capacity to replicate by cell division and can stay stem cells or divide into several different forms of blood cells and grow. Throughout your lifetime, the HSC contained in the bone marrow can build fresh blood cells.
Your destroyed stem cells are replaced with healthy cells by a bone marrow transplant. To prevent diseases, bleeding complications, or anemia, this makes the body make enough white blood cells, platelets, or red blood cells. Good stem cells, whether they can come from your own organs, can come from a donor. In such cases, before you undergo chemotherapy or radiation treatment, stem cells may be harvested or grown. In transplantation, those healthy cells are then preserved and used.
Do you Know about Bone Marrow Transplant?
It is possible to use a bone marrow transplant for: Safely allow large doses of chemotherapy or radiation to cure the disease by removing or rescuing the bone marrow weakened by treatment. Replace fresh stem cells with diseased or weakened marrow Providing new stem cells that can help directly destroy cancer cells
Bone marrow transplants will help individuals with a number of diseases that are both cancerous (malignant) and noncancerous (benign), including:
- Acute leukemia
- Aplastic anemia
- Bone marrow failure syndromes
- Chronic leukemia
- Hodgkin’s lymphoma
- Immune deficiencies
- Inborn errors of metabolism
- Multiple myeloma
- Myelodysplastic syndromes
- Non-Hodgkin’s lymphoma
- Plasma cell disorders
- POEMS syndrome
- Primary amyloidosis
Global Stem Cell Care is the best and the most experienced provider of stem cell treatment in Delhi, India. We have a due diligent team of experienced staff to take care of the patients.
Symptoms of Bone Marrow Transplant
Bone marrow transplant is considered a major medical procedure and increases your risk of experiencing:
- A drop in blood pressure
- A headache
- Shortness of breath
- A fever
- Typically, the aforementioned signs are short-lived, but complications may be caused by a bone marrow transplant. Your chances for these complications to occur depend on many factors, including:
- Your generation
- Your general wellbeing
- Disease for which you are being handled
- The sort of transplant received by you. There can be minor to very severe risks, and these may include:
- Graft-versus-host disease (GVHD), a disorder in which the body is invaded by donor cells
- Graft failure, which happens when transplanted cells do not start to create new cells as expected.
- Bleeding of the lungs, the brain and other body parts
- Cataracts, marked by clouding of the eye lens,
- Harm to crucial organs
- Early menopause
- Anemia, which happens when not enough red blood cells are produced by the body
- Sickness, diarrhea, or vomiting
- Mucositis, which is a disease that causes mouth, tongue, and stomach inflammation and soreness.
Get Stem Cell Therapy for Bone Marrow Transplant
Bone Marrow Transplant Types :
Allogeneic bone marrow transplant
Good stem cells are drawn from someone else in this form of transplant (a donor). This donor may be someone who belongs to your family or who is not related to you. The donor marrow tissue is tested for viability and only when the tissues are a fit is the transplant performed. In the method of bone marrow collection or stem cell harvesting, the stem cells are separated from the donor. The stem cells may be removed from the bone marrow of the donor, or the blood of the donor.
The umbilical cord blood donation is one form of allogeneic bone marrow transplant. In this, the stem cells which are in a newborn baby’s umbilical cord are removed as soon as the baby is born. This stem cells which have been withdrawn are frozen and stored. These may be used in the transplant process. Since these cells are very young, they are very likely to be a close match. However, as the umbilical cord stem cells are smaller, it may take longer for cell development to continue after the transplant.
Autologous bone marrow transplant
This is known as rescue transplantation, too. This is a bone marrow transplant in which, through a process called apheresis, the healthy stem cells are removed from the body. The numbers of stem cells have to be raised before apheresis is carried out.
The stable stem cells are inserted into your blood with the help of a central venous catheter that is basically a tube. This is mounted on the upper right portion of your chest, your neck or shoulder. The tube makes it possible for the stable stem cells found in the fluid to go right to the heart.
In the body, these stable stem cells then spread and ultimately develop into the bone marrow. This is where stem cell development and output by the marrow will begin. There is typically no condition that surgery be done. Global Stem Cell Care is an effective stem cell treatment provider in Delhi.
What to Expect from Stem Cell Treatment for Bone Marrow Transplant?
A bone marrow transplant’s effectiveness relies largely on how closely the donor and recipient align genetically. Often, finding a good match for unrelated donors can be very hard.
It will constantly monitor the condition of your engraftment. It is normally completed within 10 to 28 days of the original transplant. The first indication of deterioration is a growing number of white blood cells.
this means that the transplant is beginning to produce new cells in the blood.
It can take up to a year, though, for you to completely heal. Recovery relies on various considerations, including: For a bone marrow transplant, the average recovery time is around three months.
The illness being dealt with
Match for donor
Where the transplant is carried out,
There’s a chance that for the remainder of your life, any of the complications you feel following the transplant will stay with you. Stem cell treatment in Delhi offered by a reliable and experienced doctors and specialists provide you the best and the most reliable treatment
VIP Treatment to Patients at Global Stem Cell Care
- The therapy sessions given to the patients at Global Stem Cell Care occur in the VIP treatment room in the advanced clinic.
- 24*7 supervision is maintained on the patients by the efficient medical team.
- Global Stem Cell Care highly recommends the patients stay for a minimum of 3 days in Hospital.
Global Stem Cell care Treatment Procedure
- Pick up from the Airport to the Hospital
- Interaction between Dr and Patient, to clear all their doubts at that time
- Admission procedure
- Clinical examination & Lab test will be done prescribed by the doctor
- Supportive Therapy
- Stem cell Procedure
- Supportive therapies
- Supportive Therapy
- Discharging formalities
- Drop back to the Airport
- For Admission, carry the identity card (Passport/ Pan Card / Driving License)
- Carry the hard copy of Patient reports
If your bone marrow indicates an inability to produce stem cells, a bone marrow transplant may be advised by your bone marrow transplant surgeon. Bone marrow transplantation saves patients recovering from cancer-related illnesses and from extended chemotherapy and radiation exposure in the event of bone marrow injury. Your bone marrow can be revived with the aid of a bone marrow transplant after it has been destroyed, as new stem cells can speed up the development process of stem cells.
- Intravenous administration
- Liberation angioplasty
- Intrathecal (lumber puncture)
- Surgical administration for stroke
The following is the structure that is followed during the implantation stage:
A bone marrow test should be done before the beginning of your bone marrow transplantation. To decide the types of bone marrow cells that you need, the bone marrow test is used. Your bone marrow specialist will decide which treatment to take for the bone marrow exam.
If you are treated for cancer, so bone marrow aspiration and bone marrow biopsy can also be performed. He would usually ask you about your medical records and do a physical examination. This is a vital move because the doctor wants to make sure you are an acceptable candidate for the transplant process. It will take several days for this assessment period.
Phase of Conditioning
The bone marrow specialist could give you radiation or chemotherapy or both. This is performed before the treatment for transplanting bone marrow. There are two ways in which it does this.
A mini-transplant or reduced-intensity treatment is a technique in which you are given radiation and chemotherapy in lower doses. This is usually for the aged and other persons who have health problems already.
Myeloablative or ablative treatment is a method in which you are given high doses of either radiation, chemotherapy, or a mixture of these therapies. This is used to destroy cells of cancer that are in the body. Note that in this process, even healthy cells in the bone marrow that are present are destroyed.
The explanation for the conditioning mechanism is that your immune system is suppressed, cancer cells are killed (if you have a form of cancer) and your bone marrow is primed for the new stable stem cells that are about to be transplanted. There may be one or more side effects of the conditioning process, such as organ problems, weakness, hair loss, dehydration, cataracts, miscarriage, oral ulcers, and diarrhea.
Follow Up Follow Up
The follow-up is the most critical step in which the doctors determine the patient’s health. Without follow-up, it is not possible to complete the bone marrow transplant procedure. The patient needs to come to visit, according to the doctor’s advice.
Frequently Asked Questions
Yes. If they are not well enough to undergo a transplant, certain patients will not be suitable for a bone marrow transplant. The operation is very taxing on your body, and before undertaking it, overall health should also be maintained. This is why doctors devote a lot of time checking that you are physically healthy for a bone marrow transplant. A bone marrow transplant is a dangerous surgical operation, and only until they are convinced the body can withstand it can the physicians perform the procedure.
You will be closely watched by the doctors following the bone marrow transplant and they will be on the lookout for a rise in blood cell count and any pain you might feel. It may take a year to completely heal, but it depends on a number of variables. This includes, if you have an allogeneic transplant, your age, weight, radiation, chemotherapy, the disease for which you are being treated, and the donor match. If the transplant is considered successful (you are producing stem cells), you will restore your usual everyday activities.
The cost of bone marrow transplantation depends on several aspects, such as the type of transplant and when you receive the transplant. This is why the doctor will send you an estimation of the cost of bone marrow transplantation after the necessary tests are completed. Rest assured that in India, the rate of bone marrow transplantation is smaller than if you have it from other nations. In India, the cost of bone marrow transplantation can vary from hospital to hospital, so you need to do your homework online and take a quote from various hospitals before deciding to continue. However, when searching for sustainability, make sure that the standard of treatment you get is not affected.
It is dangerous to have some sort of bone marrow transplant. Typically, though, using autologous bone marrow transplantation is more effective when you use the stem cells of your own body within a donor’s cells. The big concern is the problem of incompatibility of allogeneic bone marrow transplantation. It may be impossible to find a suitable fit and there is a greater chance of complications, such as GVHD, among others. There could be a need for you to take medicines so that the donor stem cells do not end up attacking the body cells. This will make you more vulnerable to health issues.
You will start to exercise after the bone marrow transplant has become a success. It’s a good idea, though, to start slowly and then you can increase the workout intensity accordingly as you get healthier. Your doctor will support you with developing an activity routine specific to your desires and needs.