Chronic inflammatory autoimmune disease, sometimes known as lupus, is one of its many names. When lupus strikes, the symptoms may vary from the flu to organ failure. Swelling, inflammation, skin damage, and harm to key organs are just a few examples. The butterfly-shaped skin rash on a person’s face is the most prevalent symptom. Approximately 5 million individuals worldwide are affected with Lupus, and there is presently no treatment.
Lupus is caused by a variety of factors.
In most cases, Lupus is caused by a combination of genetic predisposition and environmental factors. Lupus may be more likely to develop in those with a genetic susceptibility if they are exposed to certain environmental factors. Women between the ages of 15 and 45 are more likely to be diagnosed with lupus.
Lupus symptoms might also be brought on by using certain pharmaceutical drugs.
- Hydralazine, a prescription for hypertension, is one of the most often prescribed drugs for this kind of Lupus.
There is a cardiac arrhythmia medicine known as Procainamide.
- Isoniazid, a tuberculosis-fighting antibiotic (TB)
When someone with drug-induced Lupus stops taking their medicine, it typically goes away.
Symptoms are caused by the immunological system.
Many people think of the immune system as a defence mechanism against pathogens such as bacteria and viral infections. Lupus sufferers have a hard time discriminating healthy cells from foreign antigens because of their autoimmune disorders.
Lupus Disease Signs and Symptoms
Sunlight, mild diseases, and even recommended medications might exacerbate symptoms. Immune cells in the body begin to assault the body as a result of Lupus, much like other autoimmune conditions. Large quantities of damaging inflammation may soon develop to more serious consequences as a result of this inflammatory response.
Lupus may cause organ failure, even if the most typical symptoms, such as rashes and joint discomfort, are mild and curable. Lupus has been found to cause kidney, central nervous system, circulatory system, lungs, and heart failure.
Is there a treatment for Lupus?
Lupus, like other autoimmune disorders, has no known cure and is currently being treated as such. Anti-inflammatory drugs, corticosteroids, immunosuppressants, and biologics may be administered for the patient. These strong drugs typically have negative side effects and impair the well-being of those who use them. They don’t always work to alleviate the symptoms that are already there. However, mesenchymal stem cell therapy for Lupus has shown considerable favourable effects in recent research and trials (MSCs).
Specifically, how can MSCs aid Lupus?
Known as “differentiation” or “transformation,” stem cells are young cells that develop spontaneously throughout the body. They begin by repairing and replacing cells that have been injured or inflamed. Stem cells are found in every human being. Our stem cells, on the other hand, become less effective and less plentiful as we age.